Profile change history

What changed for Emideltide?

A deterministic history of records added to PeptideScanner and preserved profile or record revisions connected through the reviewed Emideltide identity.

45Total events
44Record additions
1Version changes
13Cited source years

Before and after

Preserved version changes

Correction

Emideltide profile

We narrowed the status wording to what the dated FDA briefing establishes. A briefing prepared for an advisory process does not establish the current absence of a later final decision. Related substance identities remain distinct.

PeptideScanner change date
September 15, 2026
Evidence lane
Profile

Status

Before
FDA compounding safety review; final determination pending
After
FDA compounding assessment in the cited records

Evidence note

Before
FDA's emideltide briefing describes evidence and safety questions presented to the advisory committee. Committee recommendations are nonbinding, and FDA says its final determination will follow completion of the committee process and relevant reviews.
After
FDA's July 2026 briefing evaluates Emideltide-related bulk drug substances for pharmacy compounding. The briefing is an advisory-process assessment, not a final regulatory determination.

Claim citations

Before
name: fda-emideltide-briefing; aliases: fda-emideltide-briefing; category: fda-emideltide-briefing, fda-pcac-peptide-meeting-2026; status: fda-emideltide-briefing, fda-pcac-peptide-meeting-2026; summary: fda-emideltide-briefing, fda-pcac-peptide-meeting-2026; evidenceNote: fda-emideltide-briefing, fda-pcac-peptide-meeting-2026
After
name: fda-emideltide-briefing; aliases: fda-emideltide-briefing; category: fda-emideltide-briefing, fda-pcac-peptide-meeting-2026; status: fda-emideltide-briefing; summary: fda-emideltide-briefing, fda-pcac-peptide-meeting-2026; evidenceNote: fda-emideltide-briefing

Collection chronology

Evidence added to PeptideScanner

Browse all 44 connected records →

Showing the latest 44 additions by PeptideScanner publication date; the complete connected record set remains available in Latest Research. Most recent addition: August 21, 2026.

Record added

Federal Register notice 2026-07361

The Federal Register published notice 2026-07361, attributed to FDA and its parent HHS department, on 2026-04-16. Its official title is “Pharmacy Compounding Advisory Committee; Notice of Meeting; Establishment of a Public Docket; Request for Comments-Bulk Drug Substances Nominated for Inclusion on the Section 503A Bulk Drug Substances List,” and PeptideScanner's exact reviewed identity mapping connects the document to BPC-157, Emideltide, Epitalon, KPV, MOTS-c, Semax and TB-500.

PeptideScanner change date
August 21, 2026
Cited source date
April 16, 2026
Evidence lane
Regulatory
Record added

Immunohistochemical distribution of DSIP immunoreactivity in the human hypothalamus during the first postnatal year. A preliminary report.

PubMed lists PMID 11321250 in Folia biologica as Journal Article, with publication-date metadata of 2001 (year precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
December 30, 2025
Evidence lane
Literature metadata
Record added

Human pheochromocytoma cells studied in culture contain large amounts of DSIP-like material.

PubMed lists PMID 1800948 in Peptides as Journal Article, Research Support, Non-U.S. Gov't, with publication-date metadata of 1991 Sep-Oct (source-text precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
August 18, 2019
Evidence lane
Literature metadata
Record added

Radioimmunoassay of DSIP-like material in rat brain.

PubMed lists PMID 318193 in Brain research bulletin as Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., with publication-date metadata of 1978 Nov-Dec (source-text precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
July 19, 2019
Evidence lane
Literature metadata
Record added

DSIP--a tool for investigating the sleep onset mechanism: a review.

PubMed lists PMID 3286557 in The International journal of neuroscience as Journal Article, Review, with publication-date metadata of 1988-02 (month precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
August 28, 2019
Evidence lane
Literature metadata
Record added

Purification and characterization of DSIP-like material from ovine pineal glands: possible peptide-protein interaction.

PubMed lists PMID 3367267 in Journal of pineal research as Journal Article, Research Support, Non-U.S. Gov't, with publication-date metadata of 1988 (year precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
September 19, 2019
Evidence lane
Literature metadata
Record added

Entry of DSIP peptides into dog CSF: role of physicochemical and pharmacokinetic parameters.

PubMed lists PMID 3768731 in Brain research bulletin as Comparative Study, Journal Article, Research Support, U.S. Gov't, Non-P.H.S., with publication-date metadata of 1986-08 (month precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
July 19, 2019
Evidence lane
Literature metadata
Record added

Separation of tryptophan from DSIP, a Trp-nonapeptide, by adsorption to aluminum oxide.

PubMed lists PMID 3777433 in Analytical biochemistry as Journal Article, with publication-date metadata of 1986-09 (month precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
June 28, 2019
Evidence lane
Literature metadata
Record added

Transport of the synthetic peptide DSIP through the blood-brain barrier in rabbit.

PubMed lists PMID 590449 in Experientia as Journal Article, with publication-date metadata of 1977-12-15 (day precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
June 29, 2019
Evidence lane
Literature metadata
Record added

Content of DSIP, enkephalins and ACTH in some tissues of active and hibernating ground squirrels (Citellus suslicus).

PubMed lists PMID 6132770 in Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology as Comparative Study, Journal Article, with publication-date metadata of 1983 (year precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
August 25, 2020
Evidence lane
Literature metadata
Record added

Circadian variation of DSIP-like material in rat plasma.

PubMed lists PMID 6548540 in Life sciences as Journal Article, Research Support, U.S. Gov't, Non-P.H.S., with publication-date metadata of 1984-11-12 (day precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
July 1, 2019
Evidence lane
Literature metadata
Record added

DSIP occurs in free form in mammalian plasma, human CSF and urine.

PubMed lists PMID 6549071 in Pharmacology, biochemistry, and behavior as Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., with publication-date metadata of 1984-11 (month precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
July 12, 2019
Evidence lane
Literature metadata
Record added

DSIP-like material in brain parts of rats running a complex maze.

PubMed lists PMID 6549074 in Physiology & behavior as Journal Article, Research Support, U.S. Gov't, Non-P.H.S., with publication-date metadata of 1984-09 (month precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
July 12, 2019
Evidence lane
Literature metadata
Record added

Permeability of blood-brain barrier to DSIP peptides.

PubMed lists PMID 6895670 in Pharmacology, biochemistry, and behavior as Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S., with publication-date metadata of 1981-12 (month precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
July 12, 2019
Evidence lane
Literature metadata
Record added

Radioimmunoassay of DSIP-like material in human blood: possible protein binding.

PubMed lists PMID 6895671 in Pharmacology, biochemistry, and behavior as Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., with publication-date metadata of 1981-12 (month precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
July 12, 2019
Evidence lane
Literature metadata
Record added

DSIP-like immunoreactivity in the developing rat brain.

PubMed lists PMID 6895711 in Brain research bulletin as Comparative Study, Journal Article, Research Support, U.S. Gov't, Non-P.H.S., with publication-date metadata of 1981-12 (month precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
July 19, 2019
Evidence lane
Literature metadata
Record added

DSIP/DSIP-P and circadian motor activity of rats under continuous light.

PubMed lists PMID 6897115 in Peptides as Journal Article, with publication-date metadata of 1982 Jul-Aug (source-text precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
August 18, 2019
Evidence lane
Literature metadata
Record added

Differential penetration of DSIP peptides into rat brain.

PubMed lists PMID 6897680 in Pharmacology, biochemistry, and behavior as Journal Article, Research Support, U.S. Gov't, Non-P.H.S., with publication-date metadata of 1982-12 (month precision). PeptideScanner associated the retained record with the identity slug emideltide. These fields reproduce attributed bibliographic metadata and do not summarize or endorse the article's findings.

PeptideScanner change date
August 13, 2026
Cited source date
July 12, 2019
Evidence lane
Literature metadata
Record added

PubMed record PMID 11525128

PeptideScanner retained PubMed bibliographic metadata for PMID 11525128 at 2026-07-30T21:35:53.265Z. PubMed recorded a metadata revision date of 2016-10-20 and an Entrez history date of 2001-08-30. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
October 20, 2016
Evidence lane
Literature metadata
Record added

PubMed record PMID 16539679

PeptideScanner retained PubMed bibliographic metadata for PMID 16539679 at 2026-07-30T22:50:21.668Z. PubMed recorded a metadata revision date of 2006-11-15 and an Entrez history date of 2006-03-17. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
November 15, 2006
Evidence lane
Literature metadata
Record added

PubMed record PMID 21262293

PeptideScanner retained PubMed bibliographic metadata for PMID 21262293 at 2026-07-30T22:17:00.064Z. PubMed recorded a metadata revision date of 2011-03-18 and an Entrez history date of 2011-01-26. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
March 18, 2011
Evidence lane
Literature metadata
Record added

PubMed record PMID 2440061

PeptideScanner retained PubMed bibliographic metadata for PMID 2440061 at 2026-07-30T22:40:22.011Z. PubMed recorded a metadata revision date of 2007-01-29 and an Entrez history date of 1987-03-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
January 29, 2007
Evidence lane
Literature metadata
Record added

PubMed record PMID 3582201

PeptideScanner retained PubMed bibliographic metadata for PMID 3582201 at 2026-07-30T21:56:49.550Z. PubMed recorded a metadata revision date of 2013-11-21 and an Entrez history date of 1987-06-05. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
November 21, 2013
Evidence lane
Literature metadata
Record added

PubMed record PMID 3758119

PeptideScanner retained PubMed bibliographic metadata for PMID 3758119 at 2026-07-30T21:13:34.042Z. PubMed recorded a metadata revision date of 2018-02-14 and an Entrez history date of 1986-01-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
February 14, 2018
Evidence lane
Literature metadata
Record added

PubMed record PMID 3839701

PeptideScanner retained PubMed bibliographic metadata for PMID 3839701 at 2026-07-30T21:56:49.552Z. PubMed recorded a metadata revision date of 2013-11-21 and an Entrez history date of 1985-08-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
November 21, 2013
Evidence lane
Literature metadata
Record added

PubMed record PMID 3841224

PeptideScanner retained PubMed bibliographic metadata for PMID 3841224 at 2026-07-30T22:50:19.151Z. PubMed recorded a metadata revision date of 2006-11-15 and an Entrez history date of 1985-11-19. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
November 15, 2006
Evidence lane
Literature metadata
Record added

PubMed record PMID 6857232

PeptideScanner retained PubMed bibliographic metadata for PMID 6857232 at 2026-07-30T21:35:51.184Z. PubMed recorded a metadata revision date of 2016-10-21 and an Entrez history date of 1983-02-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
October 21, 2016
Evidence lane
Literature metadata
Record added

PubMed record PMID 6896947

PeptideScanner retained PubMed bibliographic metadata for PMID 6896947 at 2026-07-30T22:50:20.539Z. PubMed recorded a metadata revision date of 2006-11-15 and an Entrez history date of 1982-07-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
November 15, 2006
Evidence lane
Literature metadata
Record added

PubMed record PMID 6897366

PeptideScanner retained PubMed bibliographic metadata for PMID 6897366 at 2026-07-30T21:56:51.318Z. PubMed recorded a metadata revision date of 2013-11-21 and an Entrez history date of 1982-09-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
November 21, 2013
Evidence lane
Literature metadata
Record added

PubMed record PMID 6897693

PeptideScanner retained PubMed bibliographic metadata for PMID 6897693 at 2026-07-30T22:50:20.540Z. PubMed recorded a metadata revision date of 2006-11-15 and an Entrez history date of 1982-11-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
November 15, 2006
Evidence lane
Literature metadata
Record added

PubMed record PMID 7405185

PeptideScanner retained PubMed bibliographic metadata for PMID 7405185 at 2026-07-30T21:56:52.343Z. PubMed recorded a metadata revision date of 2013-11-21 and an Entrez history date of 1980-04-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
November 21, 2013
Evidence lane
Literature metadata
Record added

PubMed record PMID 8193332

PeptideScanner retained PubMed bibliographic metadata for PMID 8193332 at 2026-07-30T22:38:13.861Z. PubMed recorded a metadata revision date of 2008-10-08 and an Entrez history date of 1994-01-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
October 8, 2008
Evidence lane
Literature metadata
Record added

PubMed record PMID 8728103

PeptideScanner retained PubMed bibliographic metadata for PMID 8728103 at 2026-07-30T21:35:51.202Z. PubMed recorded a metadata revision date of 2016-11-23 and an Entrez history date of 1996-04-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
November 23, 2016
Evidence lane
Literature metadata
Record added

PubMed record PMID 891716

PeptideScanner retained PubMed bibliographic metadata for PMID 891716 at 2026-07-30T21:56:46.919Z. PubMed recorded a metadata revision date of 2013-11-21 and an Entrez history date of 1977-01-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 12, 2026
Cited source date
November 21, 2013
Evidence lane
Literature metadata
Record added

PubMed record PMID 3506231

PeptideScanner retained PubMed bibliographic metadata for PMID 3506231 at 2026-07-30T22:50:19.146Z. PubMed recorded a metadata revision date of 2006-11-15 and an Entrez history date of 1986-01-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 11, 2026
Cited source date
November 15, 2006
Evidence lane
Literature metadata
Record added

PubMed record PMID 3776352

PeptideScanner retained PubMed bibliographic metadata for PMID 3776352 at 2026-07-30T22:50:19.149Z. PubMed recorded a metadata revision date of 2006-11-15 and an Entrez history date of 1986-06-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 11, 2026
Cited source date
November 15, 2006
Evidence lane
Literature metadata
Record added

PubMed record PMID 3788358

PeptideScanner retained PubMed bibliographic metadata for PMID 3788358 at 2026-07-30T22:50:19.149Z. PubMed recorded a metadata revision date of 2006-11-15 and an Entrez history date of 1986-09-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 11, 2026
Cited source date
November 15, 2006
Evidence lane
Literature metadata
Record added

PubMed record PMID 3840534

PeptideScanner retained PubMed bibliographic metadata for PMID 3840534 at 2026-07-30T22:50:19.151Z. PubMed recorded a metadata revision date of 2006-11-15 and an Entrez history date of 1985-01-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 11, 2026
Cited source date
November 15, 2006
Evidence lane
Literature metadata
Record added

PubMed record PMID 1455954

PeptideScanner retained PubMed bibliographic metadata for PMID 1455954 at 2026-07-30T22:50:19.089Z. PubMed recorded a metadata revision date of 2006-11-15 and an Entrez history date of 1992-07-11. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 10, 2026
Cited source date
November 15, 2006
Evidence lane
Literature metadata
Record added

PubMed record PMID 2361467

PeptideScanner retained PubMed bibliographic metadata for PMID 2361467 at 2026-07-30T23:04:35.977Z. PubMed recorded a metadata revision date of 2003-11-14 and an Entrez history date of 1990-03-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 10, 2026
Cited source date
November 14, 2003
Evidence lane
Literature metadata
Record added

PubMed record PMID 2562040

PeptideScanner retained PubMed bibliographic metadata for PMID 2562040 at 2026-07-30T22:50:19.118Z. PubMed recorded a metadata revision date of 2006-11-15 and an Entrez history date of 1989-07-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 10, 2026
Cited source date
November 15, 2006
Evidence lane
Literature metadata
Record added

PubMed record PMID 6895513

PeptideScanner retained PubMed bibliographic metadata for PMID 6895513 at 2026-07-30T23:02:28.621Z. PubMed recorded a metadata revision date of 2004-11-17 and an Entrez history date of 1981-08-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 10, 2026
Cited source date
November 17, 2004
Evidence lane
Literature metadata
Record added

PubMed record PMID 7817664

PeptideScanner retained PubMed bibliographic metadata for PMID 7817664 at 2026-07-30T22:50:20.563Z. PubMed recorded a metadata revision date of 2006-04-12 and an Entrez history date of 1994-03-01. PeptideScanner associated this retained record with the identity slug emideltide. These dates describe PubMed metadata history, not the article's original publication date.

PeptideScanner change date
August 10, 2026
Cited source date
April 12, 2006
Evidence lane
Literature metadata
Record added

FDA committee met on seven peptide-related groups of bulk drug substances

FDA convened its Pharmacy Compounding Advisory Committee on July 23-24, 2026, to discuss free-base and acetate bulk drug substances across seven peptide-related groups.

PeptideScanner change date
July 29, 2026
Cited source date
July 24, 2026
Evidence lane
Regulatory