{"changeSha256":"0bc297862034fff1d6f2099717d066681cc0012f44ad6be91e27c327f570ab00","changedAt":"2026-09-15","changedFields":[{"after":"FDA compounding assessment in the cited records","before":"FDA compounding safety review","field":"Status"},{"after":"FDA's July 2026 briefing evaluates MOTS-c-related bulk drug substances for pharmacy compounding. The briefing is an advisory-process assessment, not a final regulatory determination.","before":"FDA presented MOTS-c briefing material at its July 2026 pharmacy-compounding advisory-committee meeting. Committee recommendations are nonbinding, and FDA says its final determination will follow completion of the committee process and relevant reviews.","field":"Evidence note"},{"after":"name: fda-mots-c-briefing; aliases: fda-mots-c-briefing; category: fda-bulk-peptide-risks, fda-mots-c-briefing; status: fda-mots-c-briefing; summary: fda-bulk-peptide-risks, fda-mots-c-briefing, fda-pcac-peptide-meeting-2026; evidenceNote: fda-mots-c-briefing","before":"name: fda-mots-c-briefing; aliases: fda-mots-c-briefing; category: fda-bulk-peptide-risks, fda-mots-c-briefing; status: fda-mots-c-briefing, fda-pcac-peptide-meeting-2026; summary: fda-bulk-peptide-risks, fda-mots-c-briefing, fda-pcac-peptide-meeting-2026; evidenceNote: fda-mots-c-briefing, fda-pcac-peptide-meeting-2026","field":"Claim citations"}],"currentVersion":{"canonicalUrl":"https://peptidescanner.com/peptides/mots-c/versions/3/","version":3},"id":"profile:mots-c:v3","interpretationBoundary":"This event describes a PeptideScanner public-version change. It does not by itself establish that the cited source changed, that a scientific conclusion changed, or that source monitoring is continuous.","kind":"corrected","notice":"We narrowed the status wording to what the dated FDA briefing establishes. A briefing prepared for an advisory process does not establish the current absence of a later final decision. Related substance identities remain distinct.","peptideSlugs":["mots-c"],"previousChangeEvent":{"path":"/corrections/v1/profiles/mots-c/v2.json","sha256":"041a7ad9276aaa184b9f703d248828c8826e326737200975dc550be811fe0a08"},"previousVersion":{"canonicalUrl":"https://peptidescanner.com/peptides/mots-c/versions/2/","version":2},"schemaVersion":"peptidescanner-public-correction-lineage-event/v1","sourceRecords":[{"id":"fda-mots-c-briefing","name":"U.S. Food and Drug Administration","sourceClass":"A","title":"FDA briefing document for MOTS-c","url":"https://www.fda.gov/media/193347/download","verifiedAt":"2026-07-29"}],"subject":{"slug":"mots-c","type":"profile"}}